malignancy involving the mesothelial cells of the human body, including the pleura, peritoneum, pericardium, and testis, known as malignant mesothelioma, either local or diffuse. Most, but not all, cases of malignant mesothelioma (malignant mesothelioma) in the pleural (lung cancer) is usually associated with exposure of asbestos. Patients with malignant pleural mesothelioma, 77% had been exposed to asbestos in the past. Mesothelioma diagnosis difficult to enforce because the results of the analysis of pleural fluid from cancer usually does not terdiagnostik. Mesothelioma is more common in men than women and it occurs most often in the fifth decade of age until the 7th decade. Most cases (approximately 90%) of malignant pleural mesothelioma occurred in.

Histologinya the picture there are 3 types of mesothelioma are sarcomatous mesothelioma, epithelial, and mixed (mixed). Pleural mesothelioma usually begins as plaques and nodules that combine to produce sheetlike neoplasm. Tumor growth usually begins at the bottom of the chest. Tumors can invade the surrounding surface of the diaphragm and lungs and interlobaris

Asbestos, amphibole asbestos, asbestos, crocidolite, and amosite asbestos in particular, is a major carcinogen involved in the pathogenesis. Chrysotile asbestos exposure is associated with a lower incidence of mesothelioma. Industrial area with the dikaitakan often mesotelioma result of asbestos exposure include mining industry, ship building involving the use of asbestos, asbestos cement manufacturing, ceramics, paper mill, auto parts, and repair factory train.
Clinical manifestations / symptoms that occur in the clinic mesothelioma are:
* Dyspnea and chest wall pain nonpleuritic is the most common symptoms occur in malignant mesothelioma. (Approximately 60-90% of patients had symptoms of chest pain or dyspnea.)
* In patients with malignant mesothelioma, pleural effusions physical findings are usually known by percussion and auscultation.
* In rare cases, malignant mesothelioma manifests as cord compression, brachial plexopathy, Horner syndrome, or superior vena cava syndrome. Death is usually caused by infection or respiratory failure of the development of mesothelioma.
* The main area that often occurs in the pleura (87%), peritoneum (5.1%), and the pericardium (0.4%).
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